Good Laboratory Practice (GLP) is a set of principles that guide how laboratory studies are planned, performed, monitored, recorded, reported and archived. This is different from laboratory safety standards (such as appropriate clothing). GLP helps ensure the credibility and traceability of the data presented, thus addressing the issue of non-reproducibility in many biopharmaceutical experiments. GLP aims to minimize the adverse effects of medicines and improve safety profiles for human health and the environment. GLP also helps improve accountability and data accuracy through transparent and detailed documentation of laboratory work, while assigning responsibility at various stages of the experiment. Furthermore, the International Council for Harmonization of Technical Requirements for Pharmaceutical Products for Human Use (ICH) has mentioned GLP as a prerequisite for successful international registration of pharmaceutical products. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Tips for achieving GLPImplement and/or adhere to Standard Operating Procedures (SOPs) in the laboratoryIncluding SOPs related to inspection, maintenance, calibration and testingSOP help minimize inter-individual and inter-test variability, as well as facilitate reporting of complicated proceduresSeparation of different activitiesTo minimize disturbanceLabel all reagents and solutions with name(s), date opened, storage conditions and expiry dateReagents must be used and obtained in line with relevant SOPsEnsure that all animal studies are conducted on the appropriate species This helps in correct dose selection Ensure that all techniques and instruments used are validated All data must be linked to their sources or samples Samples must be labeled with details of the patient/subject from which the sample was obtained, as specified in the SOP Document all results, not just those that favor the hypothesis Ensure that all documents are readily available for review Document any pre-set inclusion and exclusion criteria Report any excluded animals or subjects All analytical reports must be signed and dated by the relevant project manager Reports must be retained for at least 5 years Systematically archive documents so that they are readily available at all times Be familiar and up to date with all procedures (and related SOPs) required If necessary, ensure that you have or obtain the necessary certificate and qualifications needed to perform the procedure Follow good laboratory practices and techniques Be familiar with the SOPs in case of emergency and be ready to carry them out at any time Be familiar with the sheet safety data (SDS) of the chemicals used in the experiment If blood and/or urine are used, be aware of changes in the blood/urine during storage and ensure that the blood/urine is not stored for longer than necessary. changes during storage are taken into account or do not influence the results of the experiment.