Good Laboratory Practice (GLP) is a set of principles that guide how laboratory studies are planned, performed, monitored, recorded, reported and archived. This is different from laboratory safety standards (such as appropriate clothing). GLP helps ensure the credibility and traceability of the data presented, thus addressing the issue of non-reproducibility in many biopharmaceutical experiments. GLP aims to minimize the adverse effects of medicines and improve safety profiles for human health and the environment. GLP also helps improve accountability and data accuracy through transparent and detailed documentation of laboratory work, while assigning responsibility at various stages of the experiment. Furthermore, the International Council for Harmonization of Technical Requirements for Pharmaceutical Products for Human Use (ICH) has mentioned GLP as a prerequisite for successful international registration of pharmaceutical products. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Tips for achieving GLPImplement and/or adhere to Standard Operating Procedures (SOPs) in the laboratoryIncluding SOPs related to inspection, maintenance, calibration and testingSOP help minimize inter-individual and inter-test variability, as well as facilitate Reporting complicated procedures Separation of different activities To minimize disruption Label all reagents and solutions with their name(s), date opened, storage conditions and expiry date Reagents must be used and obtained in line with relevant SOPs Ensure that all animal studies are conducted on the appropriate species This helps in correct dose selection Ensure that all techniques and instruments used are validated All data must be linked to relevant sources or samples Samples must be labeled with patient/subject details to be from which the sample was obtained, as specified in the SOP. Document all findings, not just those that favor the hypothesis. Ensure that all documents are readily available for review. Document any pre-set inclusion and exclusion criteria Report any excluded animals or subjects All analytical reports must be signed and dated by the relevant project manager Reports must be retained for at least 5 years Archive documents systematically so that they are readily available at any time Be familiar and up-to-date Be up to date with all procedures (and relevant SOPs) required If necessary, ensure you have or obtain the necessary certificate and qualifications required to perform the procedure Adhere to good laboratory practices and techniques Be familiar with the SOPs in case of an emergency and be ready to perform them at any time Be familiar with the safety data sheet (SDS) of the chemicals used in the experiment If using blood and/or urine, be aware of changes in the blood/urine during the storage and ensure that the blood/urine is not stored longer than necessary ensure that changes during storage are taken into account or do not influence the results of the experiment.