Topic > The impact of the chemical DDT on human health - 884

The results of the analysis of many studies all support the working hypothesis. This means that the use of DDT is much more risky and dangerous to health to justify its use as an IRS fighting agent against malaria. The findings from each of the selected articles and journals will be described in the order of case-control studies, followed by cohort studies, then cross-sectional, and finally literature reviews. The first study is by Rignell-Hydbom; et al. considered exposure to DDT as a risk factor for type 2 diabetes. The study was conducted within a well-defined cohort of women (n = 6917) aged between 50 and 59 years from the southern Sweden. The study used 107 cases out of a total of 371 cases. They stored serum samples for at least three years before type 2 diabetes was diagnosed 17. To assess the risk of developing type 2 diabetes with DDT exposure, the study used conditional logistic regression and also used a odds ratio as a measure of risk with 95% Confidence Intervals 17. In 107/371 cases, DDT was not associated with an increased risk of developing type 2 diabetes. The study identified a series of cases (n=39) who were diagnosed more than six years after the baseline examination compared to controlled studies. Women in the highest quartile showed a greater risk of developing type 2 diabetes 17. Overall, a mean DDT concentration was found to be 46% higher than controls 17. The study produced a value of 5.5 [ 95% CI 1,2, 25] for the DDT obtained 17. Another study by the author Bräuner EV et al. looked at organochlorines in adipose tissue and the risk of non-Hodgkin lymphoma (NHL). 160,725 people aged 50 to 64 were invited to participate in the prospective Diet, Cancer and Health 2 study. A total of 57.05...... half of the paper ......ent among children 3.5 -5 years of age. Environmental health perspective. 2013 February;121(2):263-8. doi: 10.1289/ehp.1205034. Epub 2012 November 13. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/2315172222. Valvi D, Mendez MA, Martinez D, Grimalt JO, Torrent M, Sunyer J, Vrijheid M. Prenatal polychlorinated biphenyl, DDE, and DDT concentrations and overweight in children: a prospective birth cohort study. Environmental health perspective. 2012 March;120(3):451-7. doi: 10.1289/ehp.1103862. Epub 2011, October 25. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/2202755623. WHO. The use of DDT in malaria vector control. 2011. Geneva: World Health Organization. Retrieved from http://whqlibdoc.who.int/hq/2011/WHO_HTM_GMP_2011_eng.pdf24. WHO. World Malaria Report 2013. 2014. Sl: World Health Organization. Retrieved from http://apps.who.int/iris/bitstream/10665/97008/1/9789241564694_eng.pdf